Biphasic insulin aspart 30 three times daily is more effective than a twice- daily regimen, without increasing hypoglycemia, in Chinese subjects with type 2 diabetes inadequately controlled on OADs
نویسندگان
چکیده
China-Japan Friendship Hospital, Dept. Endocrinology, Beijing, China The Xijing Hospital affiliated to 4th Military Medical University, Dept. Endocrinology, Xi'an, China The Nanjing Drum Tower Hospital, Dept. Endocrinology, Nanjing, China The Beijing Tongren Hospital, Dept. Endocrinology, Beijing, China The Wuhan Union Hospital, Dept. Endocrinology, Wuhan, China The Shanghai Changzheng Hospital, Dept. Endocrinology, Shanghai, China The Metabolic Disease Hospital affiliated to Tianjin Medical University, Dept. Endocrinology, Tianjin, China Sun Yixian Commemorative Hospital affiliated to Zhongshan University, Dept. Endocrinology, Guangzhou, China
منابع مشابه
Biphasic insulin aspart 30 three times daily is more effective than a twice-daily regimen, without increasing hypoglycemia, in Chinese subjects with type 2 diabetes inadequately controlled on oral antidiabetes drugs.
OBJECTIVE To assess the efficacy and safety of twice- and thrice-daily biphasic insulin aspart 30 (BIAsp 30) in Chinese subjects with type 2 diabetes inadequately controlled with oral antidiabetes drugs (OADs). RESEARCH DESIGN AND METHODS In this 24-week, multicenter, parallel-group, randomized, treat-to-target study, 321 Chinese insulin-naïve subjects with poorly controlled type 2 diabetes (...
متن کاملInitiating insulin therapy in type 2 Diabetes: a comparison of biphasic and basal insulin analogs.
OBJECTIVE Safety and efficacy of biphasic insulin aspart 70/30 (BIAsp 70/30, prebreakfast and presupper) were compared with once-daily insulin glargine in type 2 diabetic subjects inadequately controlled on oral antidiabetic drugs (OADs). RESEARCH DESIGN AND METHODS This 28-week parallel-group study randomized 233 insulin-naive patients with HbA(1c) values >/=8.0% on >1,000 mg/day metformin a...
متن کاملSubject‐driven titration of biphasic insulin aspart 30 twice daily is non‐inferior to investigator‐driven titration in Chinese patients with type 2 diabetes inadequately controlled with premixed human insulin: A randomized, open‐label, parallel‐group, multicenter trial
AIMS/INTRODUCTION The present study was to compare the efficacy and safety of subject-driven and investigator-driven titration of biphasic insulin aspart 30 (BIAsp 30) twice daily (BID). MATERIALS AND METHODS In this 20-week, randomized, open-label, two-group parallel, multicenter trial, Chinese patients with type 2 diabetes inadequately controlled by premixed/self-mixed human insulin were ra...
متن کاملComparison of basal insulin added to oral agents versus twice-daily premixed insulin as initial insulin therapy for type 2 diabetes.
OBJECTIVE To compare the efficacy and safety of adding once-daily basal insulin versus switching to twice-daily premixed insulin in type 2 diabetic patients insufficiently controlled by oral antidiabetic agents (OADs). RESEARCH DESIGN AND METHODS In a 24-week, multinational, multicenter, open, parallel group clinical trial, 371 insulin-naive patients with poor glycemic control (fasting blood ...
متن کاملBiphasic insulin aspart 30/70 (BIAsp 30) in the treatment of type 1 and type 2 diabetes
The pharmacological advantages of the rapid-acting analog, insulin aspart, over human insulin have contributed to the widespread prescription of the premix, biphasic insulin aspart 30/70 (BIAsp 30), in type 1 (T1DM) and type 2 diabetes (T2DM). This article reviews the available literature on the pharmacology, efficacy and safety of BIAsp 30 in T1DM and T2DM from an online search of the PubMed d...
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